DPCstruct | MC61525

Metacluster Properties and Pfam Annotations

Number of structural domains210
Mean domain length (aa)276 ± 79 aa
Standard deviation of domain lengths78.91
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score85.12
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)20.18
Pfam Score94.88
Assigned Pfam label(s) PF06455- CL0425- CL0324- PF00662- CL0392

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A533ZLL3 307-593 FYLFFMNRLYVDALALRLGRGFTRVAHRLDTSRLFPYVAGLIALGLVLPAAVWTGELSAANITLFFVAALMIPLFPLHGVYVAALTR…
A0A3B1CNN1 2-208 SSLAIIGIIYGALVAMVQEDVKKLVAYSSVSHLGFVMLGIFAMNTQAIEGGMLQMINHGISTGALFLIVGVLYERRHTRLISEYGGV…
A0A4Y7JLH6 9-166 None
A0A2G4IU24 162-370 None
A0A2U2SJ41 6-452 None
A0A7V1N2K9 23-226 None
A0A6P8C2G2 39-260 None
A0A3L7Q348 45-324 None
A0A837Q744 2-191 None
A0A7C1Q440 22-176 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.