DPCstruct | MC61470

Metacluster Properties and Pfam Annotations

Number of structural domains1960
Mean domain length (aa)123 ± 27 aa
Standard deviation of domain lengths26.90
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score68.96
Mean fraction of residues predicted as intrinsically disordered0.54
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)27.86
Pfam Score96.58
Assigned Pfam label(s) PF02183- PF12045- CL0123- PF12407- CL0012

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1EKR8 1-60 RRKRTAFTHAQLQFLEKKFNCQKYLSVAERADVADGLNLTETQIKTWYQNRRTKWKRQTT
A0A6J2Y8Z7 6-127 TSQSQSVSTVQPNYHSLRLHPFGNLPTVSAYPPAVATRKQRRNRTTYSKEQLKLLEILFEKNRYPDIFMREEVAAKIRVAESRVQVW…
A0A6P4ENP8 50-172 None
A0A0C2MDK8 90-264 None
A0A6P5GDV6 70-216 None
A0A6P4E9V6 332-446 None
A0A1V2LK11 212-317 None
A0A669CZR1 51-189 None
A0A654HBM1 133-248 None
A0A1B0C357 2-113 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.