DPCstruct | MC6147

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)112 ± 9 aa
Standard deviation of domain lengths9.46
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score90.94
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)56.12
Pfam Score100.00
Assigned Pfam label(s) CL0163

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z5WWT1 102-213 LGKLHVGYSWLDFPEFNLSVVGARPFSWGSSKWKKENFYRDRYQINSFAESTQRITESVSNTKHDTVIFLGHNGPSGLGKEEYSICG…
A0A453QY17 1-123 MRPMIPFFLVNISLGEQHAGYQCLDFPTIKLSVVGGRPFSCGGDRLFRPKLLSQRYGVDDMSGSVRKIYDAATAAPEEHSVILLAHN…
A0A6V7PAA2 133-230 None
A0A287VW92 79-191 None
A0A287VW72 78-190 None
A0A0H5PQY4 12-119 None
A0A803LQH1 5-129 None
B9FRV1 88-200 None
A0A0K9QRP3 568-680 None
M4DV38 1-102 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.