DPCstruct | MC61338

Metacluster Properties and Pfam Annotations

Number of structural domains145
Mean domain length (aa)126 ± 29 aa
Standard deviation of domain lengths28.61
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score83.40
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)21.56
Pfam Score73.77
Assigned Pfam label(s) CL0039- PF03485

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376U9F2 1-109 MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFL…
A0A3B0S313 3-117 ILEELSWRVGDAFAEAGLEPHLGRVKPADRPDLAQFQCNGALAAAKAAKQNPRALAEKVCETLRREAAFKDVSIAGPGFINLTLTDD…
A0A2N1TBK4 295-410 None
A0A7S3UZQ0 254-387 None
A0A376S9F0 6-132 None
S0ET34 1-122 None
A0A536IGV7 63-177 None
A0A7V3EUR3 2-100 None
A0A537J0Y9 1-138 None
A0A2W6S2D3 5-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.