DPCstruct | MC61020

Metacluster Properties and Pfam Annotations

Number of structural domains235
Mean domain length (aa)294 ± 64 aa
Standard deviation of domain lengths64.29
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score89.45
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)19.05
Pfam Score99.73
Assigned Pfam label(s) CL0062- CL0224

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Z8D5I3 3-219 PHCAILDPTATFSLPPRQTANGVVDAFIHILEQYLTYPVNALVQDEYAEGLLRILIEEGPKALTSPQDYDIRANIMWTASQALNGIL…
A0A7C4DHH8 105-392 RWFARRLAMGGSAEELFDARLNVDDKPLSQVELAEAKIPDIELVVGIGGGMVMDMAKYVTWKRGLPLLLSPSIASVDACVTNTIAVR…
A0A7V3H3U8 26-369 None
A0A538A2J7 177-465 None
A0A484X867 22-314 None
A0A061RCK2 27-291 None
A0A850R0G3 284-675 None
A0A7V9L279 113-441 None
A0A841G1L2 8-329 None
A0A177VK47 11-279 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.