DPCstruct | MC60979

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)115 ± 10 aa
Standard deviation of domain lengths10.15
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score83.87
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)22.13
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1T3EF40 133-253 NNIKKIILDKYEKNLSFIESKKAISDTIQKGTILYSDWGYEQTNINFYLVLERKNSKLILQEIGQTRTYERQDSGTCIANPEIKKGE…
A0A373ZNT3 26-120 RRSLRVGDILYASWGWEQTNIDFYQVIAIRGSAVDLRQLDQRTTEDGYMCGTTVPLPDVFKGKTHTHRLSKNYIRIDSYRTAWKWGG…
A0A446AYP6 129-238 None
A0A1I3V3M8 20-132 None
M0DUX2 38-140 None
A0A351TN38 1-129 None
A0A077NNR3 8-125 None
A0A6N6NPA7 95-219 None
A0A2R4MJ31 82-191 None
A0A2S9WZ81 69-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.