DPCstruct | MC60936

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)206 ± 35 aa
Standard deviation of domain lengths35.08
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score79.44
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)33.71
Pfam Score100.00
Assigned Pfam label(s) PF12627

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0XGW2 18-237 SIQAAYLTFQSNKPSAQRSIMLMIVPLLKYNLLWSITVFSQCCFLLQDLLMNADKLLRADRPCSCDLWLGLLAFHLALVQNPQDSLV…
A0A1D6EC66 50-248 MLLVLFSKLDNFLAPNRPCHNSLWISLLAFHEALARKPCDPLIVATFALAFYLGGDMSLAVDIGKSINRQHDTGFRELLEPKVWTDK…
A0A5J5AP83 136-370 None
A0A7J0GBG0 239-354 None
A0A811MAN8 517-674 None
A0A166BVD2 174-390 None
A0A2P5XA84 34-254 None
Q8GZ55 106-339 None
A0A6A1VX62 57-216 None
A0A6J5Y4C2 295-536 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.