DPCstruct | MC60924

Metacluster Properties and Pfam Annotations

Number of structural domains401
Mean domain length (aa)287 ± 67 aa
Standard deviation of domain lengths66.52
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score87.65
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)23.90
Pfam Score99.16
Assigned Pfam label(s) CL0125- PF02609- PF04487- CL0302- PF08997

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A257M8K3 17-290 KDVARVHFCVPDVESQTTEAHLIAAGSTLTLADALEKGEIKNGFALVRPPGHHSMRVVHGNRGFCNINNMAIMVEYLRSKYGHKKIA…
A0A7J4EVI7 12-198 HHDDIKDMHKIYEIASLSAGGAIKAAKISLDKPAFALIRPPGHHASPEHCWGFCYFNNIAIAVRRLMKDKIIERAVIVDFDLHFGDG…
A0A1I8HYH6 131-483 None
A0A7Y4ZJX4 29-318 None
A0A2I2YP27 53-278 None
A0A061RA23 1-176 None
A0A3P8WLF9 14-318 None
A0A2B4SRE0 26-266 None
A0A5S6QFF0 1-229 None
E9G3W6 33-358 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.