DPCstruct | MC60876

Metacluster Properties and Pfam Annotations

Number of structural domains197
Mean domain length (aa)168 ± 32 aa
Standard deviation of domain lengths31.77
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score78.26
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)25.54
Pfam Score100.00
Assigned Pfam label(s) CL0028

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U4V3D7 2-151 MGIYDTVSALSVNLPWFAQILPDNYSFHNHRISDCVLAGYHALTLDETRAAYAPERWEADETGAPHEMEQVWFSGSHADVGGHLLGH…
A0A7X3Q5H5 1-122 KYGYHAVSIDEQRKKFPANMWSEDARADHQTIEQVWFAGVHSDVGGWYREAGLSDIALDWMLNKAQAQGLRLRPGWQRRLSPDPAGR…
A0A7Y2TW96 31-197 None
A0A2A9KI50 213-341 None
A0A7T8XX74 181-355 None
A0A3N4IFN3 153-385 None
A0A1L9WUU4 25-204 None
A0A2E4H5W6 5-158 None
A0A7C1PWT8 130-319 None
A0A194V4Y5 73-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.