DPCstruct | MC60847

Metacluster Properties and Pfam Annotations

Number of structural domains156
Mean domain length (aa)103 ± 23 aa
Standard deviation of domain lengths23.36
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score85.38
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)21.48
Pfam Score97.44
Assigned Pfam label(s) CL0530- CL0072- CL0280

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A532DXR8 2-106 FLRLYLDEDVSVLVADLIRAHGFDVKTTREAQNLGHSDLEQLVFSTTEQRTLLTHNRGDFERLHTEVLHQHKPHAGILIASRRASDF…
A0A7Z9WQJ0 1-98 MRFLADESCDFAVVRTLQSERYDVLAVSEARPGVEDQYIIELAKQEGRILLTEDKDFGRLVYLAGAPEVGVILLRFPAKARGELCDA…
A0A4Y7J6N6 197-276 None
A0A1F2P6W7 2-80 None
A0A848A8X3 1-76 None
A0A832FD53 98-179 None
M2ZUU1 190-269 None
A0A1M5Q7W2 79-166 None
A0A7C1Q8T4 5-87 None
A0A450SVA8 1-84 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.