DPCstruct | MC60806

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)125 ± 24 aa
Standard deviation of domain lengths24.48
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.73
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)25.37
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A421BBL7 297-420 VVTVARVPYLPNSRAGEDVLAVDAAEPDPVLRANAEIVVHPNADDPAAWVAEAIATSHCALAVAAGDRAHFAWYTGQTWTADVPGLA…
A0A1B2HDS0 24-134 HLVVHTNDPSETALQLADIVVHDEPGETAEWLAHTLASLPGTAVVTRPISDAAWLAGTRDGHQIRFDHAGTFGPARASIALTWTTSG…
S3ZLS9 41-142 None
A0A1Q9SFW2 31-158 None
A0A291QBX1 57-184 None
A0A4Q7KDA6 319-453 None
A0A371Q619 73-223 None
A0A221W600 4-123 None
S3B986 4-163 None
A0A419HHB0 2-87 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.