DPCstruct | MC60793

Metacluster Properties and Pfam Annotations

Number of structural domains2045
Mean domain length (aa)202 ± 39 aa
Standard deviation of domain lengths39.28
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.69
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.29
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)11.18
Pfam Score72.70
Assigned Pfam label(s) CL0219- PF14951- CL0010- PF01250- PF07833

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0A7GE45 32-212 GKFVPDTRKGRVKGPVKDKRIYRDRGYCRLVVETEDGDVNVYFWDEAYEVALNDIFPGMDVEVEASRGESGYHVRSAELVRVEVDES…
A0A7X6ZFQ4 6-193 IVKATIAEFIAAAVGDTQYRLTGVITSIANGTYGNLYVRDFSGEVYVYGIKDFKDKDLKVGDIITIVGKRAEYKGTPQVGGAVLESK…
A0A532E8A4 75-229 None
A0A1Z3HTB3 1-236 None
A0A1R3KMX0 3-220 None
A0A1R3KN73 634-867 None
A0A7S2CW83 7-177 None
J8G8V2 17-198 None
W1I7R5 181-354 None
A0A812MBX3 21-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.