DPCstruct | MC60752

Metacluster Properties and Pfam Annotations

Number of structural domains68
Mean domain length (aa)161 ± 25 aa
Standard deviation of domain lengths24.90
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.68
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)32.57
Pfam Score100.00
Assigned Pfam label(s) CL0493

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W6AFV6 532-708 SGIVEPIQLSGLIENQEALAQGLDPKFVFTNPFMNNFIHIGGTGGTIMLIFAIMVFSKRSDWRAMAKMTIIPALFCVNEPLLFGLPL…
A0A645EGG5 37-213 NGSLLDPLLLVNMNENMAAANAGEDAPNIINSAFVTVFTQMGGTGGTFALILAVLLFVKYKPYKDVVNLSLAPGLFEINEPIIFGLP…
A0A357QZF6 211-392 None
B1MZ09 182-366 None
A0A5R8QIE3 338-517 None
A0A858ARE2 590-777 None
A0A116R1B7 19-192 None
A0A0R1QWJ5 16-203 None
A0A5J4J6F7 20-178 None
A0A645HF42 3-123 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.