DPCstruct | MC60744

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)72 ± 10 aa
Standard deviation of domain lengths9.75
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.48
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)45.87
Pfam Score100.00
Assigned Pfam label(s) PF01422

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1D6FEF4 65-126 ERCHRGPCDGTCRLVVTKACRCGGLKKEVPCYQELTCERKCQRLRNCGRHACKRRCCAGDCP
A0A3Q7GT95 347-412 ERCHRGPCVETCRLVVTKSCRCGSYKKQVPCHQHMTCERKCQKLRDCGKHACKRRCCDGDCPPCSE
A0A2N9GLF1 356-417 None
A0A804QIW2 378-439 None
A0A5K3ENI2 56-128 None
A0A1E3IZZ3 775-852 None
A0A183E1Y7 259-349 None
A0A445JV58 1-83 None
A0A158QE04 485-557 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.