DPCstruct | MC60735

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)144 ± 15 aa
Standard deviation of domain lengths15.40
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score82.98
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)30.09
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A3RPD0 105-220 GYVVNQIYLGAGDPDYAERAYIWGTTRFKIAEGAEFVVSADGSREIRNFAIVPDGDENFDFEGGADSAIGNAALQPIIDPSKIGRTV…
A0A5S4EPI9 111-251 DFVIQQYTLADTTDDYRVRCYVWGTGGFGLSPEATFTKDANGNLRIDNYQIRAFHDNFDFDGKGDIAAKGNAILQPRIDPSKIGRTV…
H8GI81 69-223 None
A0A7D5SEZ0 21-171 None
A0A5C0DU18 97-236 None
A0A179CZE2 105-218 None
A0A433UXI9 97-235 None
A0A2S6HGB5 108-257 None
A0A377R2L6 127-291 None
A0A844GG50 101-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.