DPCstruct | MC60727

Metacluster Properties and Pfam Annotations

Number of structural domains158
Mean domain length (aa)218 ± 61 aa
Standard deviation of domain lengths61.19
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score81.73
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)15.17
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q0UFM5 35-273 YHDNTEAMQKKHDDECDVENGNKLKQCFDECFQIKHFDSPAVMLNEDGSRPEKANQYYKAPCGTTMRVKDAAHAVGVNGIGGAVIAM…
A0A167YJ69 257-506 MPSYENAGISQLSNYQTAITKKVPDTKIVESEEDVAKEPVNKAFLNIHKIDELQLDTSLMRIDQEAEFSVLKTKFDQSMLGFNMRSE…
A0A1V6S523 161-426 None
E3R103 61-249 None
M3C4F3 36-323 None
M3D2G7 81-323 None
M3DB06 72-290 None
A0A4V1XUU4 325-549 None
A0A6A5QP15 32-294 None
A0A6A5QTR4 3-222 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.