DPCstruct | MC60701

Metacluster Properties and Pfam Annotations

Number of structural domains146
Mean domain length (aa)186 ± 31 aa
Standard deviation of domain lengths30.74
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.86
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)35.83
Pfam Score86.81
Assigned Pfam label(s) PF00521- CL0110- PF16898

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812IFY5 151-340 FVDKELVLFAKANVARAIPSMVDGFKPSQRKVLFGCFKRKLRHDVKVAQLVGYVSEHAAYHHGEMSLSETIVGMAQDFVGSNNINLL…
A0A6J0SIK9 2-162 VDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEASLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRY…
A0A816VFU0 7-188 None
A0A7R9PU81 119-273 None
A0A535VXI0 414-607 None
A0A0K0EEJ7 397-590 None
E9GC34 5-168 None
A0A521F3Y2 9-207 None
A0A1I8FBP6 30-215 None
I0X5W3 21-171 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.