DPCstruct | MC60678

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)188 ± 27 aa
Standard deviation of domain lengths27.32
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score81.62
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)33.79
Pfam Score100.00
Assigned Pfam label(s) PF14222

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q2XWM0 1-188 MPISVDPESKPGEYVLKSLFAAFATMSEHKIRVIMAEPLEKPLSKSLQRGEDLQFDQLMSTMSSLAEYCLPSILRTLFDWYKRQVGL…
A0A0R3R956 2-136 ERNINKALQIGEDTYVENLLRVLNTLCEHCLPSVLATLVSWYEKQLDRFKELSEKTAKSDEQRLAINYLFCIVLIEVLPQLHFFPTI…
A0A044V8Y5 34-220 None
A0A818C286 1-216 None
A0A7J5ZMY2 1-192 None
M5G3Z1 22-212 None
B8P2M7 272-486 None
A0A0L8GD37 32-210 None
A0A423WPT1 80-319 None
A0A7F8QC99 2-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.