DPCstruct | MC606

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)105 ± 7 aa
Standard deviation of domain lengths6.91
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score86.26
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)29.38
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1V5Y709 4-108 VSVSKIFNETPGSWGLRGDPCFWDDLKRHFENTLLPYSLDAFEAEVKRFFKDIAGKTLSGDSVYVEKYARGGMSNGMVSCSFWLEQG…
A0A7X7CHD4 1-94 MKVSEIFNDEPSQWGLRGDPYLWREMKELLKDTDMPCSIEELQILIEETYKKATGHPLTYQGHFLLDRFQHGGMSSGFISPEFWTAK…
V6AHU6 62-172 None
A0A3A4S4S3 331-429 None
A0A1Q2D0Z7 42-151 None
A0A4Q5C7X7 78-182 None
A0A543MP30 68-185 None
A0A7X8UAI6 116-214 None
A0A7K0PAH0 94-201 None
A0A6V8I9I8 212-321 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.