DPCstruct | MC60572

Metacluster Properties and Pfam Annotations

Number of structural domains116
Mean domain length (aa)162 ± 24 aa
Standard deviation of domain lengths24.49
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score81.40
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.18
Pfam Score96.08
Assigned Pfam label(s) CL0274- PF03747- PF05907- PF00375- PF02792

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S2LMC9 30-201 FRHGISASILTQPQKLGLQLKCDLDNVTNLRASGDDFRWYVQAKCTNCGQEFPDFIYVCPAERVALKDSRGDANLIIRCKFCNRVGN…
A0A1V2L672 2-123 VFHLNLKANLQGLTDLAPVDTDDSPFEYTFLIQCTSCREQHDKEITINRLEQHDLPGSRGEANFVFKCKSCGHLANASITRTSKNYT…
A0A158QYZ7 274-437 None
I2H5B8 2-181 None
A0A395J474 74-266 None
A0A7S3PPZ7 117-299 None
U6KLN9 16-173 None
A0A4Q7JWX8 753-940 None
U6JXX2 1-107 None
A0A843UL41 4-154 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.