DPCstruct | MC60508

Metacluster Properties and Pfam Annotations

Number of structural domains144
Mean domain length (aa)221 ± 44 aa
Standard deviation of domain lengths44.20
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.69
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)24.85
Pfam Score79.70
Assigned Pfam label(s) CL0039- CL0258- PF03485- CL0278

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A538CAT8 320-568 RSGTLMTGPIEDLRAAVAAAASEIGEASSAPTLERPRQAGHGDFSTNAAMLLAKSAGAPPRDIAERLAASLDVRLGDDLASYEVAGP…
A0A2X2BK86 4-175 QAFLSEKISMAMSAAGAPADSEPLVRQSAKVQFGDYQANGVMGAAKKMGIPPRQLAEKILEHLDITDIADKVEIAGPGFINIFLSPV…
A0A536IGV7 69-234 None
S0ET34 10-290 None
A0A7V5J1R8 5-169 None
A0A835IIR0 4-157 None
A0A376U9F2 9-252 None
A0A7V3AUS1 1-135 None
T2JB64 1-166 None
A0A2W6S2D3 5-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.