DPCstruct | MC60461

Metacluster Properties and Pfam Annotations

Number of structural domains133
Mean domain length (aa)115 ± 33 aa
Standard deviation of domain lengths32.86
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score82.60
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)20.13
Pfam Score82.53
Assigned Pfam label(s) CL0137- PF04032- PF15719

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A842UW59 131-226 EIARQRIRELFDQAKKMFSTDPKLSDRYVRLAKKLSMKYKVRIPQELRRRMCKHCLAYLVPDKTSQTRTKEGKVVIHCLRCGGIMRV…
A0A182T9B8 3-96 FLYQAAALMSETNPQLSATYGKLAKSIGKKAVLRMEPAIKRTLCVRCGVLLNPATTADIQDHRHKQLCYVQVNCKLCGYRKRFYNSK…
A0A1Y1UUL7 101-207 None
A0A0B6YVT4 2-70 None
A0A7M7GJI9 10-192 None
A0A7C6EI65 11-104 None
A0A1M3T2N8 4-195 None
A0A2H3C1G7 1-95 None
A0A7G7JNH9 7-132 None
A0A2H6KC46 15-160 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.