DPCstruct | MC60437

Metacluster Properties and Pfam Annotations

Number of structural domains108
Mean domain length (aa)116 ± 31 aa
Standard deviation of domain lengths31.17
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score80.65
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)30.37
Pfam Score93.10
Assigned Pfam label(s) PF00566- PF07970

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183RPJ2 10-116 LKRPNPISLPPMPTVQRSLPLNMTQWKRSLDPEGRVNRPENLREIIFNGGIENDLKPIVWKYLLGYYQWTYTAEENERLKAEKSREY…
A0A2R8QAX8 18-127 DLGPRPEMQRTGPVTMEEWAKYQDLEGRMTNLPHLKDAIFKGGLCHAVRKEAWKFLLGYFPWSSTHEERKLLQKRKTDEYFRMKLQW…
A0A446N4Y8 291-380 None
A0A7M5WZB6 95-205 None
A0A3P9K8P7 253-390 None
A0A814VXE1 165-290 None
A0A3N7G3S6 16-117 None
A0A672URZ6 371-501 None
A0A7J0G9G1 524-613 None
A0A842Z0Y4 250-332 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.