DPCstruct | MC60435

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)78 ± 9 aa
Standard deviation of domain lengths9.17
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score93.61
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)45.76
Pfam Score100.00
Assigned Pfam label(s) CL0039

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A5QW07 18-91 ADVQRVVGMKWWKPKASEELCNRLLHTIYMGVSGYSSEKTRSRAHRLADTVAANHTGMNIDHIFQAERNLSLQY
A0A5F4W7X9 383-453 GNQEVLADVRTIVNQSSYTPQDPRDLCGRILTTCYMASENSSQETCSRARELAQQIGSHHISLSIDPAVKA
A0A3M7PN21 686-764 None
E2LHM8 72-145 None
A0A1I8F9M4 180-259 None
A0A842ZIC4 1-95 None
A0A7D8YSB3 136-209 None
A0A822HW39 200-275 None
A0A067DB22 119-223 None
A0A7T8HL04 51-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.