DPCstruct | MC60433

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)158 ± 19 aa
Standard deviation of domain lengths19.21
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score81.55
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)29.07
Pfam Score100.00
Assigned Pfam label(s) PF12423

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183RGG0 238-375 RMICTNTGQMCLWEREKFMTRRFLMQDMYQKSLNKQLEDYLQESDPFWEPLEDLFIGIAPAFLRALAYRLDVDEELKIMDFIGDELG…
A0A2C9LBM5 31-167 KEGMSEVMVQLRNLENGNSWLLSRNNFINRKYLMQEMFQNYTEGDPDWNVPKEKDPFWEPVSTPVLIGTSLVYLQPLAYLIDMDESL…
A0A5A8BZD2 357-529 None
A0A7D9LLU1 6-161 None
A0A7S4ID28 3-127 None
U6K636 18-125 None
A0A1S3J029 88-243 None
A0A5K3ENU8 424-558 None
A0A5K3EQM3 165-299 None
A0A5A8EAJ8 261-426 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.