DPCstruct | MC60388

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)477 ± 85 aa
Standard deviation of domain lengths84.65
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.86
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.91
Pfam Score100.00
Assigned Pfam label(s) CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D8U515 122-605 DPETSMALASMGVKQCFNAPQDRLKYKGSDTKYQWGGHHWSMTTWNKVHIMKSVYEMGVHVVHSDMDVVWFNDPLPYFKSLLEKPVH…
R1F5W9 79-688 GNSGATEMLLNWVHHVIALRKGHAMVVACYDDGLFVHLRRLRVPAYNYSGALPPVHFRGTPFLFHRMGFLKAMTIKEVLLSGRHVLV…
M7X3X2 157-748 None
A0A2S5BBW8 704-1158 None
A0A7S3BL78 181-796 None
A0A7S0J692 109-663 None
E1ZAF1 9-473 None
A0A7S4C726 59-609 None
A0A812Q8Y2 152-572 None
A0A813GLX6 9-412 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.