DPCstruct | MC60314

Metacluster Properties and Pfam Annotations

Number of structural domains64
Mean domain length (aa)155 ± 31 aa
Standard deviation of domain lengths31.21
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.76
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)37.63
Pfam Score95.00
Assigned Pfam label(s) CL0113- CL0020- CL0363- CL0307- PF01294

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1U8P8M5 2-129 VKHNNVIPNGHFKKHWQNYVKTWFNQPARKARRRIARQKKAVRIFPRPTAGPLRPVVHGQTLKYNMKLRAGKGFTLEELKAAGISKK…
A0A5N5MVK5 3-179 PSRNGMILNPHFHKDWQKRVRTWFNQPARKLRRRKARVRRSATTTRSAPAGFSLEELKAAGISKRVARTIGIAVDPRRRNRSTESLH…
A0A4T0HSH7 49-245 None
A0A2H9TP02 9-199 None
A0A2K6GF59 2-158 None
H2ZVP1 4-124 None
A0A5F5Y728 3-146 None
A0A0D2NFH5 238-355 None
L5K7E0 7-150 None
A0A182TII9 1-123 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.