DPCstruct | MC60295

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)66 ± 7 aa
Standard deviation of domain lengths6.89
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score92.92
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)57.72
Pfam Score100.00
Assigned Pfam label(s) CL0067

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G9EMH6 1-68 MLTYSEDLEYFVPYLQQLDMESNGKSINKQGRRVDYDTGPIIWGGPGNQAQHSYYQLLCQGTLKIATV
A0A7J6MH11 342-402 LPYCQALVRFVAHIQQLDMESNGKRVTLSGHAVDYSTGMVHFGEPGTNGQHSFYQELHQGT
A0A0C2MI94 17-97 None
A0A376FFA7 31-109 None
S4MSR7 351-411 None
A0A4S8IU70 342-401 None
D7G558 111-176 None
A0A6M1HZN0 68-132 None
A0A4T0QAF2 916-976 None
A0A812LEP7 858-927 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.