DPCstruct | MC60288

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)143 ± 38 aa
Standard deviation of domain lengths38.44
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score90.80
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)31.22
Pfam Score52.50
Assigned Pfam label(s) PF12561- CL0126- PF20944

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V1UPQ1 1-126 MNITSRLKTSGTGYIQSLDSVRALAAIFVLLLHGSYGYCYSPDGDAVKKSDSYLEVKTASGNLRYRLAPSRLRSGVMNKFHINIPAS…
A0A7V8I706 203-454 DVLVPTTASSYAKCASSHQLDAQGRCYKQDPMQGGAGDQSSGYKFATFSDYNTGRMQAWIASRVLADPASSTGYSKWDSAAQARAPY…
A0A0W0PED7 859-972 None
X0RFZ7 3-136 None
A0A0N0X8Y2 2-110 None
A0A376SCB6 449-564 None
A0A2T3JC41 1123-1244 None
A0A1E7F879 745-938 None
A0A4Q0YTS3 253-380 None
A0A7S3TZT0 3-150 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.