DPCstruct | MC60273

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)186 ± 22 aa
Standard deviation of domain lengths21.77
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score66.78
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)33.25
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S4VAN2 180-376 SPPESNPPLHLYFHLDLGTIFTHDDRHAFMAEMDWPFKLTVFGSVYTLVSRGFWAKDHYWGKVLRHVNGLMGVWMHDNQHNAGHARL…
A0A0L0URB8 19-166 LFSRGFWTNNHYWCKVVRSGEGGATGVWLHDEARNEGIARLVNKDTSSIGGCQPGTSWVFYSCRWTPSEEQYVRDSISKITHDHPDA…
A0A2S4V529 180-376 None
A0A2S4V436 2-174 None
A0A2S4UKR6 559-746 None
A0A2S4UK20 320-524 None
F4R613 1-226 None
F4R2Y9 1-208 None
A0A180G3Y4 268-451 None
E3JTV8 30-182 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.