DPCstruct | MC60244

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)103 ± 12 aa
Standard deviation of domain lengths11.86
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score89.52
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)26.20
Pfam Score100.00
Assigned Pfam label(s) PF10050

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S7XJN1 2-91 EIKLIDRATIRVEDWVRMKCQFGCGGYGARLTCPPYSPTPDQTRRIIKDYKNALLIHSRNSRKIKEAVPEIERELFLKGFYKAWGMG…
A0A0E3PRU7 4-117 EDENYRLLEDKAKELGAKSLRLLPAENIVVEDRTVLKCIFGCNGYGSRVCPPFIPTVEEFKKILADYEWALLVEWNSNNVFSREVSE…
A0A0W8F6V3 9-118 None
A0A5K7ZCC8 60-167 None
A0A2V2G464 49-149 None
A0A099SJ24 2-99 None
A0A847PM22 3-95 None
A0A2M7CD08 1-76 None
A0A1M5XM61 257-352 None
E1YCV8 149-256 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.