DPCstruct | MC60224

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)148 ± 13 aa
Standard deviation of domain lengths13.04
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score84.45
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)30.75
Pfam Score100.00
Assigned Pfam label(s) CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J7MQA1 7-166 FHKSIFLCFFDSCKVISKREDVYRVVKAFASRGEWMNPDAKRFIQHLVWEQTSFLYTDLSVRDFERNGLNLTLSKREEVQRLRTQID…
A0A0F4Z6D9 74-220 AFYQAVSTDQKLRDASSEAEKLLDDFAIETSMREDLYRLVDAVLKKNEDLDPESRRLLEKEHKDYIRNGLGLPAGPQRDRFKEIKKR…
A0A2B4RWE7 17-198 None
G0T0T2 144-286 None
A0A183MXQ1 26-160 None
A0A7R8WZ97 597-735 None
A0A6I9Y8C9 1-169 None
A0A084RNU1 280-432 None
A0A835HM18 111-251 None
D3BBB4 159-308 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.