DPCstruct | MC60183

Metacluster Properties and Pfam Annotations

Number of structural domains51
Mean domain length (aa)116 ± 21 aa
Standard deviation of domain lengths20.96
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.98
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)52.98
Pfam Score97.92
Assigned Pfam label(s) CL0268- PF00572

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I3H9H0 3-101 FRGPYHFRAPSRIFWRTTKRGQAALDRLKVFDSIPQPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGEEERESQDLLPEEET…
A0A7E6DEP1 6-87 TKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQ
A0A2H4SW77 465-585 None
A0A6V7NLG6 87-177 None
A0A0E0P1H6 542-677 None
A0A7N0U6W6 38-146 None
A0A7R9KME6 134-272 None
A0A453REM1 5-67 None
A0A3Q0IU91 1-90 None
V5BAB2 148-279 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.