DPCstruct | MC6012

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)129 ± 8 aa
Standard deviation of domain lengths7.62
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score78.64
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)30.97
Pfam Score100.00
Assigned Pfam label(s) PF16095

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A182U146 70-196 HPDRSISRLLLMSYFPSGFWSRLITRVLADDQVVEAVRGLYPLPKDLLDQWPALEETPALAAHWAVWQTGLALHFGPSTVVFKMREI…
A0A1I7SKV9 1-147 DVYRRLYLLQYIPPGFWPRLTTRLLNDDKLAQIISGLFVLNDESLSLSLPNECALYADIMDALNTDKGGENRGGFDFLLWQTGVETN…
A0A2A4KAR1 213-345 None
A0A5S6PRX9 1466-1593 None
J9F815 903-1030 None
A0A3Q0IZP8 626-746 None
A0A815J5R5 311-448 None
A7T966 152-271 None
A0A0K0D872 9-126 None
A0A2G5VN11 1092-1220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.