DPCstruct | MC60098

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)271 ± 51 aa
Standard deviation of domain lengths50.64
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score88.76
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)38.98
Pfam Score88.89
Assigned Pfam label(s) CL0139- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y5IQX7 33-311 GKNICLANKETLIAGGPAIVPLAVKHGVKILPADSEHSALFQCIQGMPEGALRRIILTASGGAFRDMDLATMRELAVSDPAALHKKA…
A0A2V2EX02 74-371 EILEHAFDGADVALIAAGGFAGLAYTLRAARLGIKIALANKESLVCGGELVLNAVKKSGSDLVPVDSEHSALFQALSFRRDTPFERL…
A0A835FZQ5 70-355 None
J9Z0R9 19-281 None
A0A7J7N048 178-358 None
A0A832FSE4 2-266 None
A0A811P1F4 111-470 None
A0A836RKC9 32-253 None
A0A2V6H0K4 85-395 None
A0A7V5C3S6 79-376 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.