DPCstruct | MC60023

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)110 ± 17 aa
Standard deviation of domain lengths16.71
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score87.06
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)35.99
Pfam Score94.00
Assigned Pfam label(s) PF00696- CL0052- PF00206- PF04750

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U4V008 2-77 YAEDIEGSKAYAHALQNINLLTEDEEAQICQGLDKIRIEWDNTEFVTLSEDEDIHSSNERRLKELIGEPATKLHVG
A0A7J6IL83 1-91 MAENKLWEGRFTALSQQGIYGSIAFARANFNNGILTQHKFEEIERGLLEVGKEWEAANFKIVQGNEDTHAANERRLGEIIGKDVAGK…
A0A668VG40 2-76 None
A0A833V1R0 318-420 None
A0A535RHL1 24-128 None
A0A444UC75 80-182 None
A0A812S2A7 2-118 None
A0A438F8M3 1-132 None
A0A835TIK4 164-258 None
A0A267FNY7 13-119 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.