DPCstruct | MC60018

Metacluster Properties and Pfam Annotations

Number of structural domains152
Mean domain length (aa)171 ± 31 aa
Standard deviation of domain lengths30.51
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.73
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)25.78
Pfam Score100.00
Assigned Pfam label(s) CL0149

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F7E6D9 567-743 MNQFRMLFSTCKVPGVTRDSVVNYFRTESEGVTPIHIAVLCRGRVFVFDVMHDGGMLTPPELLRQLTYIQTTCCREADGPGVAALTT…
A0A5K3FPI4 3-168 QYRNLFNSSRIPGEVVDRHATFMESRHIVVISKGKFYTFDVFNEQDDQIPSEQLVSNLELIRNQPEHAAERPSVGVVTAMDRDSAAL…
A0A819TAP7 216-333 None
A0A817PKP6 537-707 None
A0A2C9JTD0 62-256 None
A0A4Y2U3B2 81-251 None
A0A1I8HYW7 458-637 None
A0A1I8ITG7 1-158 None
A0A7M3RLU2 97-313 None
H3AEI2 266-433 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.