DPCstruct | MC60010

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)239 ± 46 aa
Standard deviation of domain lengths45.78
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score82.16
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)24.11
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445MYA2 19-280 ITSSAYDFNTVHPAINEYAVNQSDLEDILINRLGFSKGIETVFQKEFDKMTIVQWVQLGGRMEDQPESRGVEHFFDPFETWDDAGLS…
A0A1G1G2B8 21-276 SHVLALQEETHRAININIAERTINGFSLDTYLIHNLGFIDGYKQKFGGVNASGGRVNQSIAEWLGYGGIQEDRPGSITDYIQNKPTR…
A0A7T5RJY1 1-194 None
A0A5K7YVZ6 10-279 None
A0A7C4EQV8 2-180 None
A0A5S9NVK2 22-272 None
A0A554MCW5 1-184 None
A0A7Y3U694 61-348 None
A0A1V4XJF3 16-289 None
A0A7J2KSF6 17-270 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.