DPCstruct | MC60007

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)82 ± 15 aa
Standard deviation of domain lengths15.07
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.78
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)39.30
Pfam Score95.00
Assigned Pfam label(s) CL0310- CL0671- CL0329

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Z8D3I7 5-84 QRSGKLNTYLSSKEIEHFCQLHTEDALFLEETLNKLGLSIRAWHKILRVSRTIADLENEQKIQRNHLIEALSFRAMDRLM
A0A4U1GRA1 14-104 SATIRARVVKAREPQRHRFERGEASAPVNGRLSVVDLERVAAPDRGGRRMLDLAEFPPELRGKVLRVARTIADLAGSDSVRVSHVEE…
A0A4Q5XZ51 57-130 None
A0A645J6B6 18-115 None
A0A259LU39 177-259 None
A0A0P7Z4A3 252-329 None
A0A246BCV3 636-722 None
A0A7X8J0B4 2-97 None
A0A2V9L9P0 31-99 None
A0A139BPD8 3-63 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.