DPCstruct | MC59989

Metacluster Properties and Pfam Annotations

Number of structural domains517
Mean domain length (aa)165 ± 35 aa
Standard deviation of domain lengths35.01
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score86.09
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.78
Pfam Score96.30
Assigned Pfam label(s) PF05199- CL0063- CL0221- PF00696- CL0143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q2GYY8 477-666 None
A0A2X5P9H7 2-128 None
N4UKP8 119-217 None
K5VSM4 3-103 None
K5V3Z5 165-295 None
R1EHY0 184-376 None
A0A1M7TYA0 2-123 None
A0A1B7MFJ6 16-199 None
A0A7R9AZU2 1002-1183 None
A0A7R9AU62 139-268 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.