DPCstruct | MC59989

Metacluster Properties and Pfam Annotations

Number of structural domains517
Mean domain length (aa)165 ± 35 aa
Standard deviation of domain lengths35.01
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score86.09
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.78
Pfam Score96.30
Assigned Pfam label(s) PF05199- CL0063- CL0221- PF00696- CL0143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A6QV61 246-411 None
A0A1B5L4L3 306-450 None
A0A6A2WKY4 242-361 None
I4DJX6 12-167 None
A0A1Q3J1Z2 20-161 None
A0A7X0NVT5 331-515 None
A0A2K8QTX4 338-568 None
K6U0C4 1-132 None
A0A1W4V3H7 211-410 None
A0A4Y3VPF1 1-77 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.