DPCstruct | MC59989

Metacluster Properties and Pfam Annotations

Number of structural domains517
Mean domain length (aa)165 ± 35 aa
Standard deviation of domain lengths35.01
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score86.09
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.78
Pfam Score96.30
Assigned Pfam label(s) PF05199- CL0063- CL0221- PF00696- CL0143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8UWY8 11-146 None
A0A8B6G135 204-346 None
A0A226DZQ5 348-533 None
H2Y9U2 44-193 None
B8M3J8 527-740 None
Q8MSW2 35-201 None
A0A7S3HMD3 41-219 None
A0A1M7BUZ2 4-136 None
A0A0C4E194 173-360 None
B0DJB8 27-219 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.