DPCstruct | MC59989

Metacluster Properties and Pfam Annotations

Number of structural domains517
Mean domain length (aa)165 ± 35 aa
Standard deviation of domain lengths35.01
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score86.09
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.78
Pfam Score96.30
Assigned Pfam label(s) PF05199- CL0063- CL0221- PF00696- CL0143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z1PQP5 33-125 None
A0A163JCK3 870-1104 None
A0A7T8GS97 217-346 None
B0WJG9 333-477 None
A0A135UTM7 407-601 None
A0A135UP06 464-640 None
A0A3S8U2C0 420-564 None
K1WP77 789-971 None
U5H5S7 3-155 None
A0A1Y1Z9U9 325-474 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.