DPCstruct | MC59989

Metacluster Properties and Pfam Annotations

Number of structural domains517
Mean domain length (aa)165 ± 35 aa
Standard deviation of domain lengths35.01
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score86.09
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.78
Pfam Score96.30
Assigned Pfam label(s) PF05199- CL0063- CL0221- PF00696- CL0143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Z9K795 33-194 PPNMLAYGHGYSLNIILLRPKSRGSVTINIDDPFKPPQVDLKLLSKIKDLETLLIALKEGRRILRTPAFGPMRAVEVRPEPSIESDE…
A0A1I7EGC0 66-222 LVGAELDAEIRKRTIHGVDLSISLEPLPDPKNRVTLSTTRRDPHGIACPDVYYDVGDYVRKGYEASVAQLKQIAGLFNATELNITTA…
F4PK63 6-179 None
A0A1R3KAB8 18-180 None
A0A438MZZ3 715-895 None
A0A2H3CS12 1-174 None
A0A6A6LJ66 1068-1236 None
A0A7V8VJ35 8-144 None
A0A226F233 245-367 None
A0A812NIP4 337-501 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.