DPCstruct | MC59965

Metacluster Properties and Pfam Annotations

Number of structural domains130
Mean domain length (aa)131 ± 18 aa
Standard deviation of domain lengths18.25
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score89.53
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)34.87
Pfam Score100.00
Assigned Pfam label(s) CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X4ESV0 17-127 SFRRFQYDAYCRVNELFARKLVPLLEPDDIIWVHDYHLIPLATELRRAGVTNPIGFFLHVPFPSFDALRALPPYEHLLRSMSSYDVI…
A0A377K4Y7 2-121 PFLWPAFHYRLDLVQFQRPAWDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPTPEIFNALPT…
K3WI95 49-164 None
A0A0S7DYA8 82-220 None
A0A1V9YNQ3 332-486 None
A0A6V7WJS0 142-260 None
F2SZR3 139-275 None
A0A6G1I272 268-403 None
A0A151I569 150-290 None
I2H1C3 283-419 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.