DPCstruct | MC59929

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)85 ± 2 aa
Standard deviation of domain lengths2.37
Length coefficient of variation0.03
Mean AlphaFold2 pLDDT confidence score75.88
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)65.07
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T2T5H0 175-262 NEPSKTFNLRNYLLLLARLFDQEAICYCKNAIHDKENTYRVELVSALSGGFNEVWAEFADVTFSGPSQLPQSLTRLKNKAAAFFSKQP
J0RYX1 22-105 FVFQNEPSDTFNLKKTLLVLARAFSQAAICYCQNASANEVDLIRAEPGSYGEVWDTFNGIAFSAPAQLPQFLTRLKDKVYTFFK
T0E447 79-158 None
A0A2T6UCW5 46-129 None
A0A1A9H452 181-268 None
M3RWA2 1-86 None
I9ZP31 67-155 None
M3S9S1 67-152 None
I9VUX1 100-183 None
M3R485 117-200 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.