DPCstruct | MC59928

Metacluster Properties and Pfam Annotations

Number of structural domains188
Mean domain length (aa)232 ± 41 aa
Standard deviation of domain lengths40.87
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.10
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)15.59
Pfam Score93.93
Assigned Pfam label(s) PF05406- PF09234- PF04194

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A7EFK8 5-237 FKDEIHRLKKASLHFDLVPLDEDETPKLDTYFGGKPYVTDEIEIHECKNCKKNMEFICQFMMPVKNTENKKLYSFYYCFDCVKERGE…
A0A7W9RWH5 22-226 PAPGEHTIALMMVDRSVTSDASDETRFGGLPAVNDGFRWPGCRSCGGAMQFQGQIRAPGAPHLHLLFMCANHPGECDEFLADGGGNA…
A0A6J4SI43 109-326 None
A0A7S9YIP3 30-218 None
A0A447TYH1 51-255 None
A0A355Z542 92-390 None
B8IHS4 3-158 None
A0A1M5BWY2 156-349 None
A0A7Y4ZGH0 261-454 None
A0A519NEU1 198-391 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.