DPCstruct | MC59896

Metacluster Properties and Pfam Annotations

Number of structural domains4986
Mean domain length (aa)194 ± 33 aa
Standard deviation of domain lengths33.34
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score82.40
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.33
Pfam Score88.23
Assigned Pfam label(s) PF05731- CL0692- PF11957- CL0616- PF10221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C2PWU3 729-914 None
A0A016U2J2 269-511 None
A0A0R3QBQ3 108-217 None
A0A2T1LZJ9 282-476 None
A0A368GDF7 4-176 None
A0A368FU08 255-484 None
A0A3E0NVA1 290-521 None
D3BN77 133-363 None
D3BM40 48-260 None
D3BFQ3 1-220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.