DPCstruct | MC59896

Metacluster Properties and Pfam Annotations

Number of structural domains4986
Mean domain length (aa)194 ± 33 aa
Standard deviation of domain lengths33.34
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score82.40
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.33
Pfam Score88.23
Assigned Pfam label(s) PF05731- CL0692- PF11957- CL0616- PF10221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A2JPL4 138-299 None
A0A2A2JHF3 249-446 None
A0A2A2J2D9 111-336 None
A0A7X7WAJ4 221-456 None
A0A6G1QZ00 567-755 None
A0A6G1Q937 362-576 None
A0A8B6G784 354-590 None
A0A8B6G5T0 58-230 None
A0A8B6FYG0 427-630 None
A0A8B6FVE5 175-369 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.