DPCstruct | MC59896

Metacluster Properties and Pfam Annotations

Number of structural domains4986
Mean domain length (aa)194 ± 33 aa
Standard deviation of domain lengths33.34
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score82.40
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.33
Pfam Score88.23
Assigned Pfam label(s) PF05731- CL0692- PF11957- CL0616- PF10221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S7TI98 281-445 None
A0A4Y2IUD8 87-298 None
A0A6C0GD22 177-388 None
A0A1H9Y3X1 326-510 None
A0A7J3MN35 142-338 None
A0A2V8IYT2 157-331 None
A0A6L4ZIJ8 248-403 None
A0A4P2Q1T2 260-488 None
A0A843S1I0 41-184 None
D8RA18 5-176 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.